The theme of the conference is Looking Back, Moving Forward: Challenges for the Next Decade. There will be four major streams in the conference: Basic Science; Clinical Medicine; Community and Social Research; and Epidemiology, Public Health and Prevention. As well as having world leading expertise in each of the streams, the conference will endeavour to engage participants with different sectoral interests in dialogue and the cross-fertilisation of ideas. The plenary sessions are planned to include input from multiple streams on a common theme within the one session, and there will be parallel sessions for individual streams